This study examined the effect of Mini-Anchor-Chart Strategy on Interest of different reasoning ability Basic 8 Students in Basic Science in Obudu, Cross River State. Two research questions and two hypotheses guided the study. A pre-test post-test quasi-experimental control group research design was used. Out of the 3,048 Basic 8 Students in the 32 Government schools in Obudu, 68 were drawn from intact classes of two schools using a multistage sampling. Basic Science Interest Scale (BSIS) with reliability of 0.916, was used for data collection.

Cronbach’s Alpha was used to determine the reliability coefficient of the BSIS. Mean and standard deviation were used to answer the research questions while Analysis of Covariance (ANCOVA) was used to test the null hypotheses at 0.05level of significance. The findings of the study showed that, there is a significant difference in the interest level between students taught Basic Science using Mini-Anchor-Chart Strategy and Expository Teaching in favour of MACS. However, there was no significant difference in the interest level of students taught Basic Science using MACS based on reasoning ability. Therefore, it was recommended among others that Mini-Anchor-Chart Strategy be used for Science Teaching at the Upper basic education level.