The study investigated the influence of stress and anxiety on the mental health of family caregivers of mentally-ill patients in Makurdi metropolis. Ex-post facto survey design wasused.The participants were 107 caregivers comprising of 41 (38.3%)

males and 66(61.7%)females within the age range of 16 -64 years, mean age of 33.55(SD=13.77). Perceived Stress Scale, the Manifest Anxiety Scale and the General Health Questionnaire were used for data collection. Statistical analysis involved the use of simple linear regression and multiple regressions. Findings indicated that, there was no significant influence of perceived stress on the mental of family caregivers of the mentally-ill in Makurdi metropolis. There was significant influence of anxiety on mental health among family caregivers of the mentally-ill in Makurdi metropolis. There was significant joint influence of anxiety and perceived stress on mental health among family caregivers of mentally-ill in Makurdi metropolis. Based on the findings, it was concluded that anxiety has a key role in the mental health of family caregivers of the mentally-ill patients.It was therefore recommended that efforts should be made to reduce the level of anxiety inherent in the family caregivers of the mentally-ill patients.On policy bases, it was therefore recommended that government should formulate policies that would help in assisting family caregivers of the mentally-ill patients in Benue State in particular and Nigeria at large.