This study investigated Emotional Stress, anxiety and depression among pregnant women attending antenatal clinic in Makurdi Local Government area of Benue State. The study adopted a cross-sectional survey design. A total of 248 (100%) pregnantT women attending antenatal clinic in Makurdi Local Government participated in the study. Their age ranged between 21 and 44 years. They were sampled using a purposive sampling method. Perceived Emotional stress Scale (PSS) with reliability of .853, the Hamilton Anxiety Rating Scale of .717 and Beck Depression Inventory (BDI-II) with reliability of .732 were used for data collection. Three hypotheses were formulated and tested using simple liner regression and multiple linear regression. Findings of the study revealed that, emotional stress positively influence depression among pregnant women attending antenatal clinic in Makurdi Local Government area of Benue State. The results further revealed that, anxiety also significantly influence depression among pregnant women attending antenatal clinic in Makurdi Local Government area of Benue State. Finally, the results shows that emotional stress and anxiety jointly predicted depression among pregnant women attending antenatal clinic in Makurdi Local Government area of Benue State (â =.558, P