As a nation that depends on agriculture to provide food security for its citizens, recognizing the impact of agribusiness in boosting production and improving farmers' well-being is critical. The study examines the effect of agribusiness on Irish potato farmers in Mangu Local Government Area (LGA) of Plateau State, Nigeria. A structured questionnaire was used to generate data from farmers. The study employed the Average Treatment on Treated (ATT) method of analysis to evaluate the effect of agribusiness on potato farmers' well-being. The finding showed that the coefficient of ATT is positive and the t-statistic (2.35) is greater than two (2), which clearly demonstrates that benefiting from agribusiness has a significant positive effect on Irish potato farmers' wellbeing at 5% level of significance. The study concluded that adopting agribusiness in potato farming in Mangu LGA will positively impact improving farmers' wellbeing and reduce poverty. The study recommends that the local government chairman, through the department of agriculture, should collaborate with the plateau state government to provide soft loans and grants to farmers so they can afford modern farm inputs, and they should also invest in extension workers who will teach farmers modern ways of Irish potato farming, and in turn will improve their well-being